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News Archive - Skaggs School of Pharmacy and Pharmaceutical Sciences

SDSC Simulations Reveal How a Heart Drug Molecular Switch Is Turned On and Off

March 6, 2018

The study, published in the March 5 online edition of the Proceedings of the National Academy of Sciences (PNAS), describes how the supercomputing power of Gordon, Comet, and GPU clusters, all based at the San Diego Supercomputer Center at UC San Diego, were used with improved accelerated molecular dynamics (aMD) or Gaussian aMD (GaMD) to simulate the merger of a G-protein “mimetic nanobody” to a G-protein-coupled receptor (GPCR), the largest and most diverse group of membrane receptors in animals, plants, fungi, and protozoa.

Koman Family Outpatient Pavilion Opens at UC San Diego Health on March 12

March 5, 2018

On March 12, 2018, UC San Diego Health will welcome its first patients to the Koman Family Outpatient Pavilion. Located on the La Jolla campus, the new 156,000-square-foot facility represents the most recent addition to the university’s world-class medical campus. In the past five years, UC San Diego Health has invested more than $1.3 billion dollars in patient care facilities for the community.

UC San Diego Conference to Address Alternatives to the U.S.-Mexico War on Drugs

February 2, 2018

The War on Drugs has been ongoing for several decades, yet its failure can be felt on both sides of the U.S.-Mexican border­­­­­­­­­­­­­­. In the last sixteen years, the opioid epidemic has claimed close to 125,000 lives in the U.S., whereas in Mexico the war on drugs has produced an estimated 200,000 deaths and over 30,000 disappearances in the last decade.

Macrophage Nanosponges Could Keep Sepsis In Check

January 4, 2018

Researchers at UC San Diego have developed macrophage "nanosponges"—nanoparticles cloaked in the cell membranes of macrophages—that can safely remove sepsis-causing molecules from the bloodstream. In lab tests, these macrophage nanosponges improved survival rates in mice with sepsis.

Molecular Mapping Made Easy

December 21, 2017

Every day, every inch of skin on your body comes into contact with thousands of molecules — from food, cosmetics, sweat, the microbes that call your skin home. Now researchers can create interactive 3D maps that show where each molecule lingers on your body, thanks to a new method developed by University of California San Diego and European Molecular Biology Laboratory (EMBL) researchers. The technique is published December 21 in Nature Protocols.

32 UC San Diego Professors Named Most Influential in Their Fields

December 6, 2017

Thirty two faculty members at the University of California San Diego are among the world’s most influential researchers in their fields, based on their publications over the past decade.

Six UC San Diego Professors Named 2017 AAAS Fellows

November 20, 2017

UC San Diego professors Michael Burkart, Catherine Constable, Richard Gallo, William Gerwick, Miroslav Krstic and Lorraine Pillus have been awarded the distinction of fellow by the American Association for the Advancement of Science (AAAS), the largest general science organization in the United States and publisher of the journal Science.

UC San Diego Physicist Discovers an Equation for the Control of Cell Growth

October 25, 2017

Understanding the control of cell growth has challenged biomedical researchers for decades. Efforts to meet this challenge may have received an encouraging boost, however, from University of California San Diego physics professor Terence Hwa and colleagues. Their research, published in the Oct. 25 issue of Nature, led to the surprising discovery of a mathematical equation governing the control of cell growth.

U.S. News and World Report Names UC San Diego the Globe’s 16th Best University

October 24, 2017

The University of California San Diego has been named the globe’s 16th best university by U.S. News and World Report. The campus was also recognized as the nation’s 5th best public university in the fourth annual rankings, which measure factors such as research, global and regional reputation; international collaboration; as well as the number of highly-cited papers and doctorates awarded.

The Microbial Anatomy of an Organ

October 19, 2017

University of California San Diego researchers have developed the first 3D spatial visualization tool for mapping “’omics” data onto whole organs. The tool helps researchers and clinicians understand the effects of chemicals, such as microbial metabolites and medications, on a diseased organ in the context of microbes that also inhabit the region. The work could advance targeted drug delivery for cystic fibrosis and other conditions where medications are unable to penetrate.
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