UC San Diego study supports launch of Phase I clinical trial to test a designer DNA agent — an antisense oligonucleotide that targets a gene called IRF4 — in patients with multiple myeloma.
UC San Diego researchers used brain organoids to identify two drug candidates that counteract the genetic deficiencies that cause Rett syndrome, a rare form of autism spectrum disorder.
UC San Diego researchers discovered that the makeup of a person’s gut microbiome is linked to their levels of active vitamin D, and revealed a new understanding of vitamin D and how it’s typically measured.
American Association for the Advancement of Science honors the contributions of UC San Diego leaders in astrophysics, research advocacy, organic chemistry, psychiatry and geophysics.
Triclosan, an antimicrobial found in many soaps and other household items, worsens fatty liver disease in mice fed a high-fat diet.
Researchers determined that COVID-19 transmission risk via Halloween candies is low, even when they are handled by infected people, but handwashing and disinfecting collected sweets reduces risk even further.
Treatment with a peptide that mimics the naturally occurring protein GIV prevents immune overreaction and supports a mechanism critical for survival in mouse models of sepsis and colitis, according to a UC San Diego study.
J. Silvio Gutkind, PhD, has been named chair of the Department of Pharmacology at UC San Diego School of Medicine.
Analyzing anonymized patient medical records, UC San Diego researchers discovered that cholesterol-lowering statins reduced risk of severe COVID-19 infection, while lab experiments uncovered a cellular mechanism that helps explain why.
A consortium of 12 health systems, led by UC San Diego Health, introduces COVID19questions.org, a site where clinicians, researchers, patients and the general public are invited to submit questions that could be answered by COVID-19 patient medical record data from 200+ hospitals.