People with cystic fibrosis who carry genetic variants that lower RNF5 gene expression have more mutant CFTR protein on cell surfaces. Even if the CFTR protein isn’t fully functional, it’s better than none, and may explain why some with cystic fibrosis are less prone to infection than others.
Scientists have found the most effective CRISPR shield ever discovered in viruses. They discovered a remarkable new strategy that some bacteria-killing viruses, or phages, employ: after they infect bacteria, these phages construct an impenetrable “safe room” inside of their host.
Researchers from University of California San Diego School of Medicine and the Salk Institute for Biological Studies reported a form of intermittent fasting, called time-restricted eating, improved the health of study participants who had been diagnosed with metabolic syndrome.
UC San Diego launches new Center for Fluorescence-Guided Surgery. The center builds upon Roger Tsien’s legacy, delivering a new caliber of surgical precision to treat patients with tumors and disease of all types, identifying unhealthy tissues with a fluorescent glow.
The amount of carbon in the Earth’s terrestrial ecosystems is likely to decline by about 10 percent through the year 2100, according to USGS researchers who used SDSC's 'Comet' supercomputer to conduct simulations.
UC San Diego Health named a Center of Excellence for high quality of care in treating hypertrophic cardiomyopathy.
At the current pace, gender inequity in the workplace would take more than 100 years to remedy, the Kim Center and UC San Diego want to speed up the process starting with a partnership to assess the problem and stage interventions to address inequity.
Atmospheric rivers pose a $1 billion-a-year flood risk in the West, according to a study released today.
UC San Diego bioengineers developed a method that would enable them to understand how E. coli coordinate their expression of thousands of genes. The method uses a machine learning algorithm to automatically interpret gene expression datasets.
UC San Diego MFA student Juliana Kleist-Méndez is at the helm of "Elektra," the last fall-quarter production for the Department of Theatre and Dance. The sold-out run opens Dec. 4.