UC San Diego researchers found that the chemical inhibitor K777 reduces the coronavirus’ ability to infect cell lines by blocking human enzyme cathepsin L; clinical trials are underway.
By summer 2020, well into the COVID-19 pandemic, Nicaragua’s hospitals were full of patients with respiratory infections. Doctors and nurses were dying. The health system was collapsing. Yet the government has consistently downplayed the COVID-19 pandemic.
UC San Diego researchers discovered that patient survival from sepsis is associated with higher platelet counts, and identified two currently available drugs that protect these blood cells and improve survival in mice with sepsis.
By analyzing the FDA database of adverse drug effects, UC San Diego researchers discovered that people who received Botox injections — not just in the forehead — reported depression significantly less often than patients undergoing different treatments for the same conditions.
SDSC's Sherlock Division has expanded its multi-Cloud solution, Sherlock Cloud, to include the Google Cloud Platform (GCP) in addition to AWS and Microsoft Azure.
UC San Diego researchers recently created a pharmacophore model and conducted data mining of the conformational database of FDA-approved drugs that identifies 64 compounds as potential inhibitors of the COVID-19 protease.
The San Diego Supercomputer Center at UC San Diego is providing priority access to its high-performance computer systems and other resources to researchers advancing our understanding of the virus and efforts to develop an effective vaccine in as short a time as possible.
U.S. News & World Report today released its 2021 guidebook that ranks the nation’s top graduate programs and professional schools, giving praise to the University of California San Diego’s innovative programs, including the campus’ Jacobs School of Engineering and School of Medicine.
The San Diego Supercomputer Center at UC San Diego has announced the launch of ‘HPC Share’, a data sharing resource that will enable users of the Center’s high-performance computing resources to easily transfer, share, and discuss their data within their research teams and beyond.
A comparison of normal and germ-free mice revealed that as much as 70 percent of a mouse’s gut chemistry is determined by its gut microbiome. Even in distant organs, such as the uterus or the brain, approximately 20 percent of molecules were different in the mice with gut microbes.