In a survey, UC San Diego researchers report most patients are willing to share medical records for research purposes, with a few caveats.
University of California San Diego School of Medicine researchers identified a new therapeutic approach in mouse models that halts drug resistance and cancer progression by using an antibody that induces the immune system via macrophages to seek and kill cancer cells.
UC San Diego School of Medicine has been awarded $9 million to fund research projects using human pluripotent stem cells, CRISPR and human organoids to dissect beta cell defects and create a human cell model of type 1 diabetes aimed at identifying the cellular actions leading to disease onset.
UC San Diego researchers discovered that removing a single enzyme in mice dramatically boosts survival from sepsis, an often fatal over-reaction of the immune system to infection. The finding provides a new and unexpected therapeutic target for new drug development.
The multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice by reaching stem cells at the tumor’s root, according to a new UC San Diego School of Medicine study published in Science Translational Medicine.
In a Phase III clinical trial, the drug volanesorsen significantly reduced blood fat (triglyceride) levels in participants with a rare disease called familial chylomicronemia syndrome; finding could also help inform better prevention methods and treatments for many types of heart disease.
The heart transplant program at UC San Diego Health has demonstrated the best one-year survival rate for patients in the United States among health care providers with a volume of more than 50 heart transplants per year, according to the Scientific Registry of Transplant Recipients.
UC San Diego Health has been recognized among the nation’s best hospitals for 2019-20 by U.S. News & World Report. The annual “Best Hospitals” rankings are designed to assist patients and their doctors in making informed decisions about where to receive care for challenging health conditions.
A genome-wide association study of more than 165,000 U.S. veterans confirms a genetic vulnerability to post-traumatic stress disorder, specifically noting abnormalities in stress hormone response and/or functioning of specific brain regions.
UC San Diego researchers have used the transcriptome — the sum of all messenger RNA (mRNA) molecules expressed from genes — to map protein-gene interactions involved in Alzheimer’s disease.