A comparison of normal and germ-free mice revealed that as much as 70 percent of a mouse’s gut chemistry is determined by its gut microbiome. Even in distant organs, such as the uterus or the brain, approximately 20 percent of molecules were different in the mice with gut microbes.
A new study at UC San Diego, published February 11, 2020, found that exposure to heatwaves during the last week of pregnancy was strongly linked to an increased risk of preterm delivery – the hotter the temperature or the longer the heatwave, the greater the risk.
UC San Diego researchers suggest that prolonged exposure to a pair of antioxidant proteins may contribute to enlargement of the liver and fatty liver diseases.
UC San Diego announced a gift from Nissi and Ajit Varki, both professors at the university. The gift has been designated for the Center for Academic Research and Training in Anthropogeny (CARTA) to support a broad range of activities, including scholarly studies of the origins of humankind.
In a new study, researchers at University of California San Diego School of Medicine confirmed the findings of previous pilot studies that found an association between human milk concentrations and infant weight and body composition.
Researchers at UC San Diego School of Medicine report that abnormal levels of beta-amyloid plaques in brain predict cognitive decline and higher risk of developing Alzheimer’s disease, but also that cognitive performance predicts progression from normal to abnormal levels of beta-amyloid.
UC San Diego and IBM researchers reveal a new understanding of how our microbiomes change as we age, setting the stage for future research on the role microbes play in accelerating or decelerating the aging process and influencing age-related diseases.
UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.
The Protein Data Bank archive has released a new Coronavirus protease structure following the recent coronavirus outbreak, an ongoing viral epidemic primarily affecting mainland China that now threatens to spread to other parts of the world.
After identifying a molecular pathway that allows nonalcoholic steatohepatitis (NASH) to progress into liver cell death, University of California San Diego School of Medicine researchers were able to use these pathways to halt further liver damage.