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News Archive - School of Medicine

Short Overnight Fasting Linked to Increased Risk of Breast Cancer Recurrence

March 31, 2016

In patients with breast cancer, a short overnight fast of less than 13 hours was associated with a statistically significant, 36 percent higher risk of breast cancer recurrence and a non-significant, 21 percent higher probability of death from the disease compared to patients who fasted 13 or more hours per night, report University of California, San Diego School of Medicine researchers.

Successful Dying: Researchers Define the Elements of a “Good Death”

March 30, 2016

For most people, the culmination of a good life is a “good death,” though what that means exactly is a matter of considerable consternation. Researchers at the University of California, San Diego School of Medicine surveyed published, English-language, peer-reviewed reports of qualitative and quantitative studies defining a “good death,” ultimately identifying 11 core themes associated with dying well.

Remote Italian Village Could Harbor Secrets of Healthy Aging

March 29, 2016

To understand how people can live longer throughout the world, researchers at University of California, San Diego School of Medicine have teamed up with colleagues at University of Rome La Sapienza to study a group of 300 citizens, all over 100 years old, living in a remote Italian village nestled between the ocean and mountains on the country’s coast.

Stem Cells Used to Successfully Regenerate Damage in Corticospinal Injury

March 28, 2016

Writing in Nature Medicine, researchers at University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System, with colleagues in Japan and Wisconsin, report that they have successfully directed stem cell-derived neurons to regenerate lost tissue in damaged corticospinal tracts of rats, resulting in functional benefit.

For the Perfect Eggs, Roundworms Use Small RNAs

March 24, 2016

All multicellular organisms that reproduce sexually rely on eggs to support early life. Researchers at University of California, San Diego School of Medicine and Ludwig Cancer Research used the tiny roundworm C. elegans as a model to better understand how eggs enable embryonic development, using only the materials already present in them. Their study uncovers the role small RNAs and helper proteins play in fine-tuning egg development.

Genetic Changes that Cause Autism Are More Diverse Than Previously Thought

March 24, 2016

The types of gene mutations that contribute to autism are more diverse than previously thought, report researchers at University of California, San Diego School of Medicine in the March 24 online issue of The American Journal of Human Genetics. The findings, they say, represent a significant advance in efforts to unravel the genetic basis of autism spectrum disorder (ASD).

UC San Diego Health Joins National Clinical Trial on Hemophilia B Gene Therapy

March 22, 2016

The Hemophilia and Thrombosis Treatment Center at UC San Diego Health has joined a nationwide clinical trial testing a potential gene therapy that may one day provide a better and long-lasting treatment for people with hemophilia B.

Educating Community Research Facilitators Helps Protect Integrity of Study Results

March 18, 2016

A recent study by researchers at University of California, San Diego School of Medicine reports that educating community health workers and other “citizen scientists” can improve knowledge of basic research concepts and ultimately boost the integrity of scientific research.

CIRM Grant to Fund Proposed Stem Cell Trials for ALS

March 17, 2016

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine approved yesterday a $6.3 million grant to a research team from the University of California, San Diego School of Medicine and University of California, Davis to pursue a novel human embryonic stem cell-based therapy to rescue and restore neurons devastated by amyotrophic lateral sclerosis or ALS.

For First Time, Scientists Use CRISPR-Cas9 to Target RNA in Live Cells

March 17, 2016

Scientists have long sought an efficient method for targeting RNA— intermediary genetic material that carries the genetic code from the cell’s nucleus to protein-making machinery — in living cells. Researchers at University of California, San Diego School of Medicine have now achieved this by applying the popular DNA-editing technique CRISPR-Cas9 to RNA. The study is published March 17 in Cell.
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