Scientists have developed a CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new “soft” CRISPR system makes use of natural DNA repair machinery, providing a foundation for novel gene therapy strategies with the potential to cure genetic diseases.
UC San Diego researchers have created a mathematical model to help predict risk of anal cancer in persons with HIV infection and aid patients and doctors regarding screening decisions.
Using brain organoids, UC San Diego researchers discover mutational commonalities between muscular dystrophy type 1 and Rett syndrome, suggesting the potential of a similar treatment for both.
Researchers are expanding their understanding of unique immune “memory” cells equipped to remember malicious invaders. They developed an atlas that describes tissue-resident memory cells in diverse settings, boosting prospects for new immune defense strategies at vulnerable infection sites.
UC San Diego Health study identifies the main job stressors contributing to physician suicides.
In a pair of studies, UC San Diego School scientists have deepened investigations into the genetic origins of nonalcoholic fatty liver disease in children, describing multiple gene variants that contribute to disease risk.
UC San Diego researchers describe how the microbiomes of people and the homes they live in interact and change each other.
A $10 million grant over four years will support further examination of a national study looking at COVID-19 vaccination safety during pregnancy and immune response pre-and post-delivery for both mom and baby.
Findings from a new University of California San Diego Rady School of Management study reveal people often hurt others because in their mind, it is morally right or even obligatory to be violent and as a result, they do not respond rationally to material benefits.
COVID-19 rebound following Paxlovid treatment likely due to insufficient drug exposure, UC San Diego researchers find after showing rebound patient did not show drug resistance or impaired immunity.