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News Archive - Anne Doerr, Dana-Farber Cancer Institute

Alternative Proteins Encoded by Same Gene Have Widely Divergent Functions

February 11, 2016

A single human gene can produce many different proteins. In the first large-scale study of its kind, researchers at University of California, San Diego School of Medicine, Dana-Farber Cancer Institute and McGill University report that most of these sibling proteins encoded by the same gene — known as protein isoforms — often play radically different roles within tissues and cells.
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