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News Archive - Christina Johnson

Compounds in Desert Creosote Bush Could Treat Giardia and “Brain-eating” Amoeba Infections

August 15, 2017

Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego and the University of Colorado Anschutz Medical Campus have found that compounds produced by the creosote bush, a desert plant common to the Southwestern United States, exhibit potent anti-parasitic activity against the protozoa responsible for giardia infections and an amoeba that causes an often-lethal form of encephalitis.

For White Middle Class, Moderate Drinking Is Linked to Cognitive Health in Old Age

August 1, 2017

Older adults who consume alcohol moderately on a regular basis are more likely to live to the age of 85 without dementia or other cognitive impairments than non-drinkers, according to a University of California San Diego School of Medicine-led study.

UC San Diego Health Named among Nation’s “Most Wired”

July 10, 2017

UC San Diego Health has been named one of the nation’s “Most Wired” health systems by Hospitals & Health Networks magazine, a publication of the American Hospital Association. The award recognizes hospitals and health systems that excel in using information technology (IT) to advance patient care and population health, protect the privacy and security of patient information, and bring greater efficiencies to operations.

Rapid Testing for TB Aims to Reduce Drug Resistance, Lower Mortality Rate

September 3, 2015

Researchers at University of California, San Diego School of Medicine have documented the accuracy of three new tests for more rapidly diagnosing drug-resistant forms of tuberculosis (TB), which are much harder and more expensive to treat and which, experts say, represent a major threat to global public health.

Smoking Cessation Drug Not Boosting Number of Smokers Who Quit

August 17, 2015

The introduction of a new prescription smoking-cessation aid, varenicline, in 2006 has had no significant impact on the rate at which Americans age 18 and older successfully quit smoking, according to a study led by researchers at University of California, San Diego School of Medicine. The findings, published online August 17 in Tobacco Control, suggest that the primary effect of varenicline has been to displace the use of older tobacco addiction therapies, such as nicotine patches and the antidepressant, bupropion.

New Drug for Blood Cancers Now in Five Phase II Clinical Trials

July 27, 2015

Researchers at University of California, San Diego School of Medicine have established the safety and dosing of a new drug for treating blood cancers. The findings are published online July 27 in The Lancet Haematology.

Protein’s Impact on Colorectal Cancer is Dappled

June 30, 2015

Researchers at University of California, San Diego School of Medicine have discovered a cell signaling pathway that appears to exert some control over initiation and progression of colorectal cancer, the third leading cause of cancer-related death in the United States. A key protein in the pathway also appears to be predictive of cancer survival rates.

How to Reset a Diseased Cell

May 1, 2015

In proof-of-concept experiments, researchers at University of California, San Diego School of Medicine demonstrate the ability to tune medically relevant cell behaviors by manipulating a key hub in cell communication networks. The manipulation of this communication node, reported in this week’s issue of Proceedings of the National Academy of Sciences, makes it possible to reprogram large parts of a cell’s signaling network instead of targeting only a single receptor or cell signaling pathway.

Novel Approach Blocks Amyloid Production in Alzheimer’s Mouse Model

April 29, 2015

Offering a potential early intervention for Alzheimer’s disease (AD), researchers at University of California, San Diego School of Medicine and Cenna Biosciences, Inc. have identified compounds that block the production of beta amyloid peptides in mice. The study is reported April 29 in PLOS ONE.


Golgi Trafficking Controlled by G-Proteins

April 9, 2015

A family of proteins called G proteins are a recognized component of the communication system the human body uses to sense hormones and other chemicals in the bloodstream and to send messages to cells. In work that further illuminates how cells work, researchers at University of California, San Diego School of Medicine have discovered a new role for G proteins that may have relevance to halting solid tumor cancer metastasis.
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