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News Archive - Scott LaFee

Mitochondrial DNA Mutations Linked to Heart Disease Risk

August 4, 2022

UC San Diego and Salk Institute researchers report a surprising link between mitochondria, inflammation and gene mutations that may increase risk of atherosclerosis.

Engineering the Microbiome to Potentially Cure Disease

August 4, 2022

UC San Diego researchers report using native bacteria in mice as the chassis for delivering transgenes capable of inducing persistent and potentially even curative therapeutic changes in the gut and reversing disease pathologies.

Gene Therapy Approach Shows Promise in Treating ALS

August 2, 2022

Researchers report that a gene therapy approach, developed at UC San Diego measurably delayed disease onset in humanized mouse and rat models of familial ALS, an inherited form of the disease that runs in families.

Iron Buildup in Brain Linked to Higher Risk for Movement Disorders

August 1, 2022

UC San Diego researchers report that individuals with two copies of a gene mutation show evidence of substantial iron buildup in regions of the brain, raising risk for movement disorders like Parkinson’s disease.

Lactating Mice Pass along Common Antimicrobial to Pups, Initiating Liver Damage

July 27, 2022

In mouse studies, UC San Diego researchers report that lactating mothers expose their feeding pups to triclosan, an antimicrobial commonly used in consumer products, resulting in early signs of liver damage.

Coronavirus Jumped to Humans at Least Twice at Market in Wuhan, China

July 26, 2022

In a pair of related studies, UC San Diego researchers show that the origin of the COVID-19 pandemic was at a Chinese market and resulted from at least two instances of the SARS-CoV-2 virus jumping from live animal hosts to humans working or shopping there.

Coronavirus Jumped to Humans at Least Twice at Market in Wuhan, China

July 26, 2022

In a pair of related studies, UC San Diego researchers show that the origin of the COVID-19 pandemic was at a Chinese market and resulted from at least two instances of the SARS-CoV-2 virus jumping from live animal hosts to humans working or shopping there.

A Novel COVID-19 Vaccine Using Modified Bacterial DNA

July 21, 2022

UC San Diego researchers describe a different way to build a COVID-19 vaccine, one that would, in theory, remain effective against new and emerging variants and could be taken as a pill, by inhalation or other delivery methods.

Post-COVID Lung Disease Shares Origins with Other Scarring Lung Disorders

July 20, 2022

UC San Diego researchers provide first insights into the fundamental cellular pathologies that drive interstitial lung disease in patients post-COVID.

How Mitochondrial Damage Ignites the “Auto-Inflammatory Fire”

July 13, 2022

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and well-being.
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