Scientists have developed a CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new “soft” CRISPR system makes use of natural DNA repair machinery, providing a foundation for novel gene therapy strategies with the potential to cure genetic diseases.
Researchers are expanding their understanding of unique immune “memory” cells equipped to remember malicious invaders. They developed an atlas that describes tissue-resident memory cells in diverse settings, boosting prospects for new immune defense strategies at vulnerable infection sites.
School of Biological Sciences neurobiologist Yishi Jin and molecular biologist James T. Kadonaga have been elected to the National Academy of Sciences, one of the highest honors bestowed upon U.S. scientists and engineers.
Using second-long electrical shocks, UC San Diego scientists were able to control the types of cells in a community of bacteria. Being able to direct the ratio of cells holds implications for settings spanning agriculture to health care, where antibiotic resistance is a significant threat.
Two global leaders are joining strengths in a broad new effort to advance the discovery and innovation needed to address complex scientific challenges. UC San Diego and Thermo Fisher Scientific have agreed to form a transformational 10-year strategic partnership.
Within the University of California system, the student population of 294,000 is an expanding kaleidoscope of experiences and backgrounds: nearly 40 percent are first-generation university students… 34 percent come from low-income backgrounds… 27 percent are racial and ethnic minorities.
UC San Diego scientists have developed a method for tracking the invasive Asian giant “murder” hornet’s presence and possibly accelerate its removal. The researchers identified the Asian giant hornet queen’s sex pheromone, an achievement that could be used as bait to trap and track the insects.
Scientists at UC San Diego and Rutgers University have found intriguing new details about a previously missing critical factor in gene expression. An ancient protein called NDF found in all human tissues enhances gene activation and may be involved in diseases such as cancer.
The salinity of freshwater ecosystems caused by road de-icing salts, agriculture fertilizers, mining operations and climate change is increasing worldwide and current water quality guidelines don’t do enough to address the issue, an international study with UC San Diego scientists has found.
Common flies feature more advanced cognitive abilities than previously believed. Using a custom-built immersive virtual reality arena, neurogenetics and real-time brain activity imaging, researchers found attention, working memory and conscious awareness-like capabilities in fruit flies.