Scientists have developed a CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new “soft” CRISPR system makes use of natural DNA repair machinery, providing a foundation for novel gene therapy strategies with the potential to cure genetic diseases.
Researchers are expanding their understanding of unique immune “memory” cells equipped to remember malicious invaders. They developed an atlas that describes tissue-resident memory cells in diverse settings, boosting prospects for new immune defense strategies at vulnerable infection sites.
UC San Diego researchers fared well in this year’s Multidisciplinary University Research Initiative (MURI) competition, held annually by the Department of Defense. The DOD has announced MURI awards for two UC San Diego-led research teams and three teams of which UC San Diego researchers are a part.
University of California San Diego alumnus David Goeddel, ’72, and his wife Alena, have donated $7.5 million to drive leading-edge research, discovery and training in the UC San Diego School of Biological Sciences, which includes support for the newly named Goeddel Family Technology Sandbox.
School of Biological Sciences neurobiologist Yishi Jin and molecular biologist James T. Kadonaga have been elected to the National Academy of Sciences, one of the highest honors bestowed upon U.S. scientists and engineers.
Using second-long electrical shocks, UC San Diego scientists were able to control the types of cells in a community of bacteria. Being able to direct the ratio of cells holds implications for settings spanning agriculture to health care, where antibiotic resistance is a significant threat.
The Kavli Foundation has given $5 million to UC San Diego for the Kavli Institute for Brain and Mind, matching the gifts of generous donors including Joan and Irwin Jacobs; William and Marisa Rastetter; Sandra Timmons ’81 and Rick Sandstrom ’72, Ph.D.
Humankind faces catastrophic changes in climate patterns, sea level, ocean acidity, public health, and worldwide ecosystems due to climate change. According to the most recent assessment from the United Nations Intergovernmental Panel on Climate Change, if there’s any hope of mitigating the worst outcomes,…
Stephen Mayfield, a molecular biology professor at UC San Diego, now has a stake in the business of footwear alongside partners Michael Burkart and Robert Pomeroy from the Department of Chemistry and Biochemistry. We spoke with Mayfield about how he gets his inspiration.
Two global leaders are joining strengths in a broad new effort to advance the discovery and innovation needed to address complex scientific challenges. UC San Diego and Thermo Fisher Scientific have agreed to form a transformational 10-year strategic partnership.