New research has uncovered a protein that enables the replication of arenaviruses, lethal pathogens spreading in West Africa. The research identified DDX3 as a key factor through its unexpected ability to dismantle normal human immune system defenses. The study may pave the way to new therapeutic treatments…
Researchers discovered an unexpected twist in the battle versus tumors. Tumors employ a protein called PD-L1 to blind T cells from functioning. PD-L1 protects tumors through a “molecular brake” known as PD-1. Researchers have found that some tumor cells display not only their PD-L1 weapon, but also…
Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric,…
UC San Diego has selected Kit Pogliano, a professor of molecular biology, as its new dean for the Division of Biological Sciences. Pogliano was selected after a national search and will begin her new appointment on Sept. 15, 2018. She is the fourth dean of the division and its first female leader. She…
With microbial resistance to antibiotics growing into a major global health crisis, researchers at University of California San Diego School of Medicine, in collaboration with national research institutions and private industry, are leveraging hard-won expertise to exploit a natural viral enemy of pathogenic…
The Pew Charitable Trusts has announced that UC San Diego Biological Sciences Assistant Professors Matthew Daugherty and Enfu Hui have been selected to the 2018 class of Pew Scholars in the Biomedical Sciences. Pew also announced that Diego Alvarez and Grisel Cruz Becerra, Biological Sciences postdoctoral…
Graphene electrodes could enable higher quality imaging of brain cell activity thanks to new research by a team of engineers and neuroscientists at the University of California San Diego. The researchers developed a technique, using platinum nanoparticles, to lower the impedance of graphene electrodes…
A team led by researchers at UC San Diego’s Department of Chemistry and Biochemistry and SDSC has used machine learning techniques to develop models for simulations of water with “unprecedented accuracy.” Published online in The Journal of Chemical Physics, the research demonstrates how popular…
Neglected tropical diseases are a group of chronic and disabling parasitic infections that primarily affect poor and underserved communities. These diseases affect more than 1 billion people globally, yet are rarely the target of new drug discovery efforts. Leveraging its strengths in molecular biology,…
A UC San Diego-led team has identified a gene that helps prevent the harmful buildup of proteins that can lead to neurological disorders such as Alzheimer’s and Parkinson’s disease. As published in Nature, the researchers found that the “Ankrd16” gene acts like a failsafe in proofreading and…