UC San Diego scientists have provided promising new evidence that the “planar cell polarity,” a powerful signaling pathway, is a widely used mechanism for the formation and maintenance of a large number of synapses.
Biological Sciences Associate Professor Elizabeth Villa has been selected as a 2021 Howard Hughes Medical Institute (HHMI) Investigator. As one of 33 scientists chosen out of pool of more than 800, Villa will receive $9 million over a seven-year HHMI Investigator term.
Using a virus that grows in black-eyed pea plants, researchers developed a new therapy that could keep metastatic cancers from spreading to the lungs, as well as treat established tumors in the lungs.
The National Institutes of Health has awarded a $12.25 million grant to the University of California San Diego to develop and enhance brain-sensing and brain-stimulating platform technologies to enable treatment of drug-resistant epilepsy.
New visualizations of SARS-CoV-2 have allowed researchers to discover how the virus enters and infects healthy human cells. They found that glycan sugar molecules act as infection “gates” to our cell’s receptors.
Neurobiologists have uncovered the mechanisms behind the maintenance and decline of key synapses implicated in Alzheimer’s disease. The findings suggest an alternative approach to addressing such brain disorders.
“When will we get ‘back to normal?’” is a question looming on many Americans’ minds. The answer largely depends on the country’s ability to substantially ramp up immunity to SARS CoV-2.
UC San Diego researchers and their colleagues have discovered that spontaneous impulses of dopamine, the neurological messenger known as the brain’s “feel good” chemical, occur in the brain of mice. The study found that mice can willfully manipulate these random dopamine pulses for reward.
Research reveals that phage viruses that undergo special evolutionary training increase their capacity to subdue bacteria. The results provide hope for the antibiotic resistance crisis, a rising threat as deadly bacteria continue to evolve to render many modern drugs ineffective.
Scientists have developed a gene drive with a built-in genetic barrier that is designed to keep the drive under control. The researchers engineered synthetic fly species that, upon release in sufficient numbers, act as gene drives that can spread locally and be reversed if desired.