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News Archive - School of Medicine

Researchers Develop New Strategy to Target KRAS Mutant Cancer

September 13, 2017

In a new study, published this month in Cancer Discovery, University of California San Diego School of Medicine researchers report that approximately half of lung and pancreatic cancers that originate with a KRAS mutation become addicted to the gene as they progress.

These Mutations Could Be Key to Understanding How Some Harmful Conditions Develop

September 12, 2017

A team of researchers led by a bioinformatician at the University of California San Diego has developed a method to help determine whether certain hard-to-study mutations in the human genome, called short tandem repeats or microsatellites, are likely to be involved in harmful conditions. The team, which also includes scientists from the New York Genome Center, Harvard University, and the Massachusetts Institute of Technology, details their findings in the Sept. 11 issue of Nature Genetics.

When Ancient Fossil DNA Isn’t Available, Ancient Glycans May Help Trace Human Evolution

September 11, 2017

Researchers at University of California San Diego School of Medicine and collaborators discovered a new kind of glycan (sugar chain) that survives even in a 4 million-year-old animal fossil from Kenya, under conditions where ancient DNA does not. While ancient hominin fossils are not yet available for glycan analysis, this proof-of-concept study, published September 11 in Proceedings of the National Academy of Sciences, sets the stage for unprecedented explorations of human origins and diet.

New UC San Diego Master’s Degree Will Train Professionals for Drug Development Careers

September 6, 2017

The Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego now offers a Master of Science in Drug Development and Product Management. This is the pharmacy school’s first master’s degree program. The program is intended for experienced professionals to gain managerial and regulatory knowledge required to lead all aspects of the drug development process, from discovery to clinical application in managed markets.

Zika Virus Targets and Kills Brain Cancer Stem Cells

September 5, 2017

In developing fetuses, infection by the Zika virus can result in devastating neurological damage, most notably microcephaly and other brain malformations. In a new study, published today in The Journal of Experimental Medicine, researchers at the University of California San Diego School of Medicine and Washington University School of Medicine in St. Louis report the virus specifically targets and kills brain cancer stem cells.

Boosting Immune Cell Memory to Improve Vaccines and Cancer Immunotherapy

August 28, 2017

In mouse experiments, researchers at University of California San Diego School of Medicine have discovered that drugs that activate the cells’ proteasome, or recycling center, tip the balance in favor of memory CD8+ T cells. This approach could be used to improve how well vaccines and immunotherapies work and how long they last.

It’s Not a Rat’s Race for Human Stem Cells Grafted to Repair Spinal Cord Injuries

August 28, 2017

More than one-and-a-half years after implantation, researchers at University of California San Diego School of Medicine and the San Diego Veterans Administration Medical Center report that human neural stem cells (NSCs) grafted into spinal cord injuries in laboratory rats displayed continued growth and maturity, with functional recovery beginning one year after grafting.

Breakthrough Clinical Psychology Program Funded by UC San Diego Alumnus

August 25, 2017

Joseph Edelman, founder and CEO of life science-focused hedge fund Perceptive Advisors, feels that poor mental health affects not only one’s personal well-being, but that of those around them and the entire economy “because people are more productive when they’re happier.” Two years ago, this belief led him to donate $400,000 to increase mental health services to students at the University of California San Diego.

State’s Stem Cell Agency Awards $18.2 Million Grant for B Cell Cancer Clinical Trial

August 24, 2017

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine (CIRM) today unanimously approved an $18.29 million grant to University of California San Diego School of Medicine researchers to fund a phase Ib/IIa clinical trial of a novel combination drug therapy for B-cell cancers.

Help UC San Diego Scientists Study Link between Body Bacteria and Autoimmune Diseases

August 23, 2017

The public's help is being enlisted in the Microbiome Immunity Project, what's thought to be the biggest study to date of the human microbiome — the communities of bacteria and other microbes that live in and on the human body, where they influence our health.
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