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News Archive - School of Medicine

GERD Study Offers Minimally Invasive Procedure at No Cost

September 21, 2015

Approximately 20 million Americans will experience some type of gastroesophageal reflux disease, or GERD, in their lives. In some cases, patients suffer resulting heart burn or acid regurgitation so severe that they require surgery to repair damage to their esophagus. A clinical trial at UC San Diego Health is using a new, FDA-approved device that reconstructs the esophagus through the mouth and requires no incisions.

Down Syndrome Research Untangles Therapeutic Possibilities for Alzheimer’s

September 17, 2015

More than five million Americans are living with Alzheimer’s disease (AD). Of them, 400,000 also have Down syndrome. Both groups have similar looking brains with higher levels of the protein beta amyloid. In fact, patients with Down syndrome develop the abnormal protein at twice the rate. Results of a pilot study confirms the pathogenic role of beta amyloid in dementia as seen in both AD and Down syndrome.

Reduced Heart Rate Variability May Indicate Greater Vulnerability to PTSD

September 10, 2015

A prospective longitudinal study of U.S. Marines suggests that reduced heart rate variability – the changing time interval between heartbeats – may be a contributing risk factor for post-traumatic stress disorder (PTSD). The findings are reported in the September 9 online issue of JAMA Psychiatry by researchers at the University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System.

Identified Genetic Interaction Offers Possible New Target for Glaucoma Therapy

September 10, 2015

Scientists at the University of California, San Diego School of Medicine have elucidated a genetic interaction that may prove key to the development and progression of glaucoma, a blinding neurodegenerative disease that affects tens of millions of people worldwide and is a leading cause of irreversible blindness.

San Diego Events Map Future of Brain Research and Remedies

September 8, 2015

Two University of California, San Diego-sponsored events in September, over two consecutive Saturdays, highlight the importance of a comprehensive approach to brain research. First, on Sept. 12, is an education and advocacy forum for the public bringing together those affected by Alzheimer's disease, Parkinson's disease, brain injury, stroke, epilepsy, autism, mental illness or depression. Then on Sept. 19 a research symposium will connect local “neurotechnology” innovators to one another and to the region’s business community.

Stem Cell-derived “Mini-brains” Reveal Potential Drug Treatment for Rare Disorder

September 8, 2015

Using “mini-brains” built with induced pluripotent stem cells derived from patients with a rare, but devastating, neurological disorder, researchers at University of California, San Diego School of Medicine say they have identified a drug candidate that appears to “rescue” dysfunctional cells by suppressing a critical genetic alteration.

Rapid Testing for TB Aims to Reduce Drug Resistance, Lower Mortality Rate

September 3, 2015

Researchers at University of California, San Diego School of Medicine have documented the accuracy of three new tests for more rapidly diagnosing drug-resistant forms of tuberculosis (TB), which are much harder and more expensive to treat and which, experts say, represent a major threat to global public health.

Targeting Newly Discovered Pathway Sensitizes Tumors to Radiation and Chemotherapy

September 3, 2015

In some patients, aggressive cancers can become resistant to chemotherapy and radiation treatments. In a paper published in the journal Nature Communications, University of California, San Diego School of Medicine researchers identified a pathway that causes the resistance and a new therapeutic drug that targets this pathway.

UC San Diego Health to Manage Emergency Services at El Centro Regional Medical Center

September 2, 2015

From comprehensive stroke care when every second counts to stitching deep cuts and evaluating flu symptoms, UC San Diego Health provides the highest quality of care when patients arrive through the emergency room doors. Now, as part of a long term partnership between UC San Diego Health and El Centro Regional Medical Center (ECRMC), patients in the Imperial Valley will receive the same specialty emergency care.

UC San Diego Scientists Investigate Global Hemorrhagic Fever Bacterial Disease

September 1, 2015

An international research team, headed by Joseph Vinetz, MD, professor of medicine at University of California, San Diego School of Medicine and director of the UC San Diego Center for Tropical Medicine and Travelers Health, has been awarded a 5-year, $1.89 million cooperative agreement to carry out translational research studies of leptospirosis, an infectious and sometimes fatal bacterial disease endemic in much of the world.
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